Filling Line Isolators

FILLING MACHINE ISOLATORS ARE DESIGNED...

to enclose the filling, stoppering and capping operations of a Powder or Liquid Filling Machine while providing an aseptic environment for the process, achieving ISO 5 grade A classification. This isolator allows for the entry of pre-sterilized stoppers and caps through a Rapid Transfer Port (RTP). Powder is also presented into the Isolator via the RTP. Glassware is transferred to the isolator in separate transfer isolators. The Transfer Isolator “docks” to the filling isolator via a RTP and the trays of glassware are manually positioned on the accumulator of the filling machine. The vials are automatically moved by the filling machine through the filling, stoppering and capping stations and exit through a “mouse hole” in the end wall of the isolator. A conveyor carries the vials from the Isolator under an external unidirectional airflow module and into the adjoining packaging room.

Local Operator Panel (LOP)
Cap entry shoot
Filling Line Isolator

ENGINEERED CONTAINMENT SOLUTIONS

CUSTOM DESIGN

We know that not all customer requirements will fall into a standard isolator design.

For that reason we offer custom designed filling isolators to suit individual customer requirements with full third party filling equipment integration.

Design Advantages

CLASSIFICATION

ISO5 - Grade A

within unidirectional airflow system

DECONTAMINATION

Fully

Integrated Hydrogen Peroxide system

Design advantages

Ergonomically designed oval glove ports
316L stainless steel construction
PLC control
Positive pressure airflow system with HEPA filtration and a self-contained unidirectional airflow system
Special “mouse hole” protected by unidirectional airflow for exit of filled vials
Integrated Hydrogen Peroxide decontamination
Temperature control to maintain the Isolator at ambient temperature with high/low set points.

Available options

RTP system for sterile liquid entry/ vial introduction /stopper, cap & product introduction
Automatic negative pressure breach ventilation system (available for potent aseptic filling applications)
Connection to an external vial washer (separate piece of equipment) on the exit of the isolator
Air recirculatory within windows
Clean in place systems
Safe change filters
Full validation services available including IQ/OQ protocols.